In the top right corner of the interface there is a small button with a question mark, when clicking on this you will open up the Lyris ListManager™ Help manual.
To get help for a page you are viewing in Lyris ListManager™, click on the question mark on that page. This button appears only if there is a help topic for that page. You can also browse the help topics, search for specific text or find text in the Index using the navigation pane on the left.